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ATR 抗体

This anti-ATR antibody is a 兔 多克隆 antibody detecting ATR in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7254349
发货至: 中国

Quick Overview for ATR 抗体 (ABIN7254349)

抗原

See all ATR 抗体
ATR (ATR serine/threonine kinase (ATR))

适用

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宿主

  • 43
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克隆类型

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多克隆

标记

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This ATR antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human ATR

    亚型

    IgG
  • 应用备注

    IHC 1:40-1:200, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.1 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ATR (ATR serine/threonine kinase (ATR))

    别名

    ATR

    背景

    The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.

    UniProt

    Q13535

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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