Leptin Receptor 抗体
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- 抗原 See all Leptin Receptor (LEPR) 抗体
- Leptin Receptor (LEPR)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Leptin Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human LEPR
- 亚型
- IgG
- Top Product
- Discover our top product LEPR Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.84 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Leptin Receptor (LEPR)
- 别名
- LEPR (LEPR 产品)
- 背景
- The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 133 kDa
- UniProt
- P48357
- 途径
- JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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