ERH 抗体
Quick Overview for ERH 抗体 (ABIN7253677)
抗原
See all ERH 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human ERH
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亚型
- IgG
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anti-Enhancer of Rudimentary Homolog (ERH) (AA 1-104) antibody
ERH 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-Enhancer of Rudimentary Homolog (ERH) (Center) antibodyERH 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Rudimentary Homolog (ERH) (AA 2-104) antibodyERH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Rudimentary Homolog (ERH) (C-Term) antibodyERH 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Rudimentary Homolog (ERH) (AA 1-104) antibodyERH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Enhancer of Rudimentary Homolog (ERH) (AA 1-30), (N-Term) antibodyERH 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:40-1:200, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.96 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ERH (Enhancer of Rudimentary Homolog (ERH))
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别名
- ERH
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背景
- ERH (enhancer of rudimentary homolog), also known as DROER, is a 104 amino acid transcriptional coregulator that is ubiquitously expressed and highly conserved among eukaryotes. ERH may play a role in cell cycle regulation and pyrimidine biosynthesis. ERH represses the function of the coactivator PCBD, preventing it from enhancing the activity of the tissue-specific transcription factor HNF-1 (hepatocyte nuclear factor-1). HNF-1 is a homeodomain transcription factor that binds DNA as a dimer and the HNF-1/DNA complex is stabilized by PCBD. By repressing PCBD, ERH disrupts the stability of the HNF-1/DNA complex, affecting the expression of multiple genes in the liver. The structure of ERH is characterized by a single domain consisting of three alpha-helices and four beta-strands. ERH has a long flexible loop that is significantly conserved, suggesting that this loop region may be important for the function of ERH. ERH has two casein kinase II phosphorylation sites that are thought to disrupt the ability of ERH to dimerize.
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UniProt
- P84090
抗原
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