Syntaxin 5 抗体
Quick Overview for Syntaxin 5 抗体 (ABIN7252510)
抗原
See all Syntaxin 5 (STX5) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human STX5
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亚型
- IgG
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anti-Syntaxin 5 (STX5) (AA 1-100) antibody
STX5 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A6 unconjugated
anti-Syntaxin 5 (STX5) (AA 1-101) antibodySTX5 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5A6 unconjugated
anti-Syntaxin 5 (STX5) (AA 55-355) antibodySTX5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 5 (STX5) (AA 180-209) antibodySTX5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB17857 unconjugated
anti-Syntaxin 5 (STX5) (AA 179-209), (Middle Region) antibodySTX5 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.14 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Syntaxin 5 (STX5)
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别名
- STX5
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背景
- The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa ("long") protein localized to the Golgi complex and endoplasmic reticulum, and a ""short"" 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 40 kDa
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UniProt
- Q13190
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途径
- Transition Metal Ion Homeostasis, Regulation of Cell Size, Synaptic Vesicle Exocytosis
抗原
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