C1orf124
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy3
应用备注
IHC 1:50-1:300, ELISA 1:5000-1:10000
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
Spartan (C1orf124)
(Chromosome 1 Open Reading Frame 124 (C1orf124))
别名
SPRTN
背景
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.