VASP 抗体
Quick Overview for VASP 抗体 (ABIN7252180)
抗原
See all VASP 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
 - Polyclonal Antibody
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纯化方法
 - Antigen affinity purification
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免疫原
 - Fusion protein of human VASP
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亚型
 - IgG
 
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应用备注
 - WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 0.5 mg/mL
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缓冲液
 - PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Avoid freeze / thaw cycles.
 
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- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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别名
 - VASP
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背景
 - Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 40 kDa
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UniProt
 - P50552
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途径
 - TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
 
抗原
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