FKBPL 抗体
Our Local Distributor
北京 101111
Quick Overview for FKBPL 抗体 (ABIN7252003)
抗原
See all FKBPL 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Antigen affinity purification
-
免疫原
- Fusion protein of human FKBPL
-
亚型
- IgG
-
-
anti-FK506 Binding Protein Like (FKBPL) (AA 1-349) antibody
FKBPL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) (AA 1-347) antibodyFKBPL 适用: 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) (AA 264-292), (C-Term) antibodyFKBPL 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25528 unconjugated
anti-FK506 Binding Protein Like (FKBPL) (AA 1-349) antibodyFKBPL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) (AA 1-349) antibodyFKBPL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) antibodyFKBPL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) (Internal Region) antibodyFKBPL 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) (AA 71-120) antibodyFKBPL 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein Like (FKBPL) (N-Term) antibodyFKBPL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC 1:30-1:150, ELISA 1:2000-1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.3 mg/mL
-
缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- FKBPL (FK506 Binding Protein Like (FKBPL))
-
别名
- FKBPL
-
背景
- FKBPL,also named as DIR1,NG7 and WISp39,has similarity to the immunophilin protein family,which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is thought to have a potential role in the induced radioresistance,probably by increasing the rate of DNA repair in cells exposed to X rays. Also it appears to have some involvement in general stress response in the control of the cell cycle. It regulates p21 protein stability by binding to Hsp90 and p21. Breast cancer cells stably overexpressing FKBPL became dependent on estrogen for their growth and were dramatically more sensitive to the antiestrogens tamoxifen and fulvestrant,whereas FKBPL knockdown reverses this phenotype. FKBPL is an estrogen-inducible gene that acts as a cochaperone in ERα/Hsp90 Molecular complexes, furthermore,FKBPL levels may be both a prognostic indicator and determinant of response to endocrine therapy.
-
UniProt
- Q9UIM3
抗原
-
