CASP4 p20 (Cleaved-Gln81) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in ELISA, IHC (p) 和 WB. Suitable for 人.
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Quick Overview for CASP4 p20 (Cleaved-Gln81) 抗体 (ABIN7251298)
抗原
CASP4 p20
适用
人
宿主
兔
克隆类型
多克隆
应用范围
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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抗原表位
- Cleaved-Gln81
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from the Internal region of human Caspase-4 p20
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CASP4 p20
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背景
- This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
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分子量
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Observed_MW: 43+22 kDa
Calculated_MW: 43 kDa
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UniProt
- P49662
抗原
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