GSK3 alpha/beta 抗体
Quick Overview for GSK3 alpha/beta 抗体 (ABIN7251145)
抗原
适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human GSK3alpha/beta around the non-phosphorylation site of Tyr279/216.
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亚型
- IgG
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anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (pTyr216), (pTyr279) antibody
GSK3a/b 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (Ser4520) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠, 非洲爪蟾 WB, IHC, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (Center) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (pTyr216), (pTyr279) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b) (AA 246-295), (pTyr279) antibodyGSK3a/b 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
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别名
- GSK3 alpha/beta
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背景
- Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3 kinase/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3βGSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus and mammalian development. GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization.
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分子量
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Observed_MW: 51,46 kDa
Calculated_MW: 51 kDa
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UniProt
- P49840, P49841
抗原
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