MLKL 抗体 (pSer358)
Quick Overview for MLKL 抗体 (pSer358) (ABIN7250983)
抗原
See all MLKL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer358
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产品特性
- Phosphorylated antibody
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纯化方法
- Protein A purification
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免疫原
- Synthetic Peptide of Phospho-MLKL (Ser358)
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亚型
- IgG
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anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibody
MLKL 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (Internal Region) antibodyMLKL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472), (C-Term) antibodyMLKL 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (N-Term) antibodyMLKL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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别名
- MLKL
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背景
- This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain, however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.MLKL (Mixed Lineage Kinase Domain Like Pseudokinase) is a Protein Coding gene. Among its related pathways are Apoptosis and Autophagy and CDK-mediated phosphorylation and removal of Cdc6. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity.
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UniProt
- Q8NB16
抗原
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