Filamin A 抗体 (pSer2152)
Quick Overview for Filamin A 抗体 (pSer2152) (ABIN7250800)
抗原
See all Filamin A (FLNA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer2152
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human Filamin 1 around the phosphorylation site of Ser2152
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Filamin A (FLNA) (Filamin A, alpha (FLNA))
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别名
- FLNA
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背景
- The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: 280 kDa
Calculated_MW: 281 kDa
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UniProt
- P21333
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途径
- TCR Signaling, Maintenance of Protein Location
抗原
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