PI3K p85 alpha/gamma 抗体 (pTyr199, pTyr467)
Quick Overview for PI3K p85 alpha/gamma 抗体 (pTyr199, pTyr467) (ABIN7250758)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr199, pTyr467
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产品特性
- Phosphorylated antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from human PI 3-kinase p85/p55 around the phosphorylation site of Tyr467/199
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亚型
- IgG
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anti-Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g) (pTyr199), (pTyr467) antibody
PI3K p85a/g 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g) antibodyPI3K p85a/g 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g) (pTyr199), (pTyr467) antibodyPI3K p85a/g 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g) (Ser106) antibodyPI3K p85a/g 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g) (AA 436-485) antibodyPI3K p85a/g 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PI3K p85 alpha/gamma (PI3K p85a/g) (Phosphoinositide 3 Kinase, p85 alpha/gamma (PI3K p85a/g))
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别名
- PI 3 kinase p85 alpha /gamma
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背景
- The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
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分子量
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Observed_MW: 55+85 kDa
Calculated_MW: 54+83 kDa
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UniProt
- P27986, Q92569
抗原
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