Iba1 抗体
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北京 101111
Quick Overview for Iba1 抗体 (ABIN7249968)
抗原
See all Iba1 (IBA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Monoclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse IBA-1
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亚型
- IgG
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应用备注
- IHC 1:200-1:800
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.4 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
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别名
- AIF1
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背景
- This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
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UniProt
- O70200
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途径
- Smooth Muscle Cell Migration
抗原
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