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Glutathione Peroxidase 1 抗体

GPX1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7249606
发货至: 中国
  • 抗原 See all Glutathione Peroxidase 1 (GPX1) 抗体
    Glutathione Peroxidase 1 (GPX1)
    适用
    • 75
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    • 15
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    小鼠, 大鼠
    宿主
    • 63
    • 13
    • 4
    • 1
    克隆类型
    • 61
    • 20
    多克隆
    标记
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    This Glutathione Peroxidase 1 antibody is un-conjugated
    应用范围
    • 60
    • 30
    • 26
    • 22
    • 18
    • 15
    • 14
    • 13
    • 12
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    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse GPX1
    亚型
    IgG
    Top Product
    Discover our top product GPX1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    400 μg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Glutathione Peroxidase 1 (GPX1)
    别名
    GPX1 (GPX1 产品)
    别名
    Gpx antibody, ATGPX1 antibody, F13D4.40 antibody, F13D4_40 antibody, GLUTATHIONE PEROXIDASE 1 antibody, glutathione peroxidase 1 antibody, gshpx1 antibody, AI195024 antibody, AL033363 antibody, CGPx antibody, GPx-1 antibody, GSHPx-1 antibody, GPX1 antibody, gpx1 antibody, cb690 antibody, zgc:92737 antibody, zgc:103683 antibody, GPXD antibody, GSHPX1 antibody, GSHPx antibody, wu:fd42f12 antibody, wu:fj22d06 antibody, zgc:101700 antibody, glutathione peroxidase Gpx1 antibody, glutathione peroxidase antibody, glutathione peroxidase 1 antibody, glutathione peroxidase 1a antibody, glutathione peroxidase family protein antibody, proliferating cell nuclear antigen antibody, glutathione peroxidase 1b antibody, glutathione peroxidase 1 S homeolog antibody, gpx1 antibody, GPX1 antibody, gpx antibody, Gpx antibody, Gpx1 antibody, gpx1a antibody, POPTR_0003s12620g antibody, Pcna antibody, LBL_RS00590 antibody, btuE-1 antibody, GPX2 antibody, gpx1b antibody, gpx1.S antibody
    背景
    The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population. The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women. Alternatively spliced transcript variants have been found for this gene. Pseudogenes of this locus have been identified on chromosomes X and 21.
    分子量

    Observed_MW: 22 kDa

    Calculated_MW: 22 kDa

    UniProt
    P11352, P04041
    途径
    Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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