Glutathione Peroxidase 1 抗体
Quick Overview for Glutathione Peroxidase 1 抗体 (ABIN7249606)
抗原
See all Glutathione Peroxidase 1 (GPX1) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse GPX1
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亚型
- IgG
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anti-Glutathione Peroxidase 1 (GPX1) (AA 50-203) antibody
GPX1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 164-193), (C-Term) antibodyGPX1 适用: 人, 小鼠, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB22987 unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (Internal Region) antibodyVerified GPX1 适用: 人, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 50-203) antibodyGPX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 116-146), (Middle Region) antibodyGPX1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 48-201) antibodyGPX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 127-193) antibodyGPX1 适用: 人 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 169-199), (C-Term) antibodyGPX1 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 51-150) antibodyGPX1 适用: 人, 小鼠, Pig, 绵羊 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 1 (GPX1) (AA 48-201) antibodyGPX1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 400 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Glutathione Peroxidase 1 (GPX1)
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别名
- GPX1
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背景
- The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance, therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population. The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women. Alternatively spliced transcript variants have been found for this gene. Pseudogenes of this locus have been identified on chromosomes X and 21.
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分子量
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Observed_MW: 22 kDa
Calculated_MW: 22 kDa
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UniProt
- P11352, P04041
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途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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