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DOK3 抗体

This anti-DOK3 antibody is a 兔 多克隆 antibody detecting DOK3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7249172
发货至: 中国

Quick Overview for DOK3 抗体 (ABIN7249172)

抗原

See all DOK3 抗体
DOK3 (Docking Protein 3 (DOK3))

适用

  • 45
  • 31
  • 5

宿主

  • 62
  • 3
  • 1

克隆类型

  • 65
  • 1
多克隆

标记

  • 31
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DOK3 antibody is un-conjugated

应用范围

  • 50
  • 24
  • 22
  • 13
  • 13
  • 10
  • 8
  • 7
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human DOK3

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:1000-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.4 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DOK3 (Docking Protein 3 (DOK3))

    别名

    DOK3

    背景

    DOK3 gene maps to chromosome 5q35.3. Dok3 was tyrosine phosphorylated by Src family members Lck, Fyn, and Lyn. Immunoprecipitation studies showed that Dok3 bound inhibitors SHIP and Csk but did not bind RasGAP. Dok3 binding to SHIP occurred via the SH2 domain. Dok3 also bound Csk via the Csk SH2 domain with possible involvement of the Csk SH3 domain as well.DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 53 kDa

    UniProt

    Q7L591
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