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PRNP 抗体

This anti-PRNP antibody is a 兔 多克隆 antibody detecting PRNP in ELISA 和 IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7249118
发货至: 中国

Quick Overview for PRNP 抗体 (ABIN7249118)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

  • 94
  • 35
  • 34
  • 13
  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 90
  • 20
  • 3
  • 2
  • 1

克隆类型

  • 81
  • 35
多克隆

标记

  • 57
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This PRNP antibody is un-conjugated

应用范围

  • 63
  • 34
  • 27
  • 26
  • 24
  • 15
  • 12
  • 11
  • 11
  • 7
  • 6
  • 3
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human PRNP

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.6 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    PRNP

    背景

    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.

    UniProt

    P04156

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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