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KLF1 抗体

This anti-KLF1 antibody is a 兔 多克隆 antibody detecting KLF1 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7248551
发货至: 中国

Quick Overview for KLF1 抗体 (ABIN7248551)

抗原

See all KLF1 抗体
KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

适用

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  • 6
  • 5
  • 5
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宿主

  • 32
  • 12
  • 1

克隆类型

  • 34
  • 12
多克隆

标记

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  • 1
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This KLF1 antibody is un-conjugated

应用范围

  • 30
  • 23
  • 5
  • 4
  • 2
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  • 2
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human KLF1

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:100, ELISA 1:2000-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

    别名

    KLF1

    背景

    This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

    UniProt

    Q13351
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