CORO2B 抗体
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北京 101111
Quick Overview for CORO2B 抗体 (ABIN7248476)
抗原
See all CORO2B 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human CORO2B
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亚型
- IgG
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anti-Coronin, Actin Binding Protein, 2B (CORO2B) (AA 1-475) antibody
CORO2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Coronin, Actin Binding Protein, 2B (CORO2B) (AA 275-324) antibodyCORO2B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Coronin, Actin Binding Protein, 2B (CORO2B) (AA 62-111) antibodyCORO2B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Coronin, Actin Binding Protein, 2B (CORO2B) (C-Term) antibodyCORO2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coronin, Actin Binding Protein, 2B (CORO2B) (C-Term) antibodyCORO2B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-1:5000, IHC 1:40-1:200, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.5 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CORO2B (Coronin, Actin Binding Protein, 2B (CORO2B))
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别名
- CORO2B
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背景
- Coronins are a family of WD repeat-containing, actin-binding proteins that localize to submembraneous areas and regulate cell motility and cytoskeletal rearrangement. Coronin 1A (CORO1A, CLIPINA, CLABP, TACO, p57) can form coiled coil-mediated homotrimeric complexes that influence early phagosome formation. PKC-dependent phosphorylation of Coronin 1B (CORO1B) at Serine 2 regulates leading edge dynamics and cell motility in fibroblasts through interactions with Arp2/3 complex. Coronin 1C (CORO1C, Coronin 3, HCRNN4) is abundant in differentiating Neuro-2a cells, PC-12 cells and primary oligodendrocytes, where it is thought to influence neuron morphogenesis and migration. Coronin 2A (CORO2A, CLIPINB, IR10, WDR2) is a component of the approximately 1.5-2 megadalton N-CoR (nuclear receptor corepressor) complex of 10-12 proteins, which recruits HDACs to generate repressive chromatin. Coronin 7 (CORO7, CRN7) localizes to the Golgi membrane and influences the organization of intracellular membrane compartments and vesicular trafficking. Coronin 2B (CORO2B, CLIPINC) and Coronin 6 (CORO6) are similar to other members of this family, since they possess a conserved basic N-terminal motif and 3-10 WD repeats clustered in one to two core domains.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 55 kDa
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UniProt
- Q9UQ03
抗原
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