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PIWIL2 抗体

This anti-PIWIL2 antibody is a 兔 多克隆 antibody detecting PIWIL2 in IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7004802
发货至: 中国

Quick Overview for PIWIL2 抗体 (ABIN7004802)

抗原

See all PIWIL2 抗体
PIWIL2 (Piwi-Like 2 (PIWIL2))

适用

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人, 小鼠

宿主

  • 19
  • 3
  • 1

克隆类型

  • 21
  • 2
多克隆

标记

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This PIWIL2 antibody is un-conjugated

应用范围

  • 21
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Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human PIWIL2

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.7 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PIWIL2 (Piwi-Like 2 (PIWIL2))

    别名

    PIWIL2

    背景

    PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when repressed. When overexpressed, acts as an oncogene by inhibition of apoptosis and promotion of proliferation in tumors

    UniProt

    Q8TC59

    途径

    Stem Cell Maintenance
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