CEND1 抗体
Quick Overview for CEND1 抗体 (ABIN7248425)
抗原
See all CEND1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human CEND1
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亚型
- IgG
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anti-Cell Cycle Exit and Neuronal Differentiation 1 (CEND1) (N-Term) antibody
CEND1 适用: 人, 小鼠, 大鼠, 马, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle Exit and Neuronal Differentiation 1 (CEND1) (N-Term) antibodyCEND1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Cycle Exit and Neuronal Differentiation 1 (CEND1) (N-Term) antibodyCEND1 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.9 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
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别名
- CEND1
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背景
- BM88, also known as CEND1 (cell cycle exit and neuronal differentiation protein 1), is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 15 kDa
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UniProt
- Q8N111
抗原
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