ZNF828 抗体
Quick Overview for ZNF828 抗体 (ABIN7248329)
抗原
See all ZNF828 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human CHAMP1
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亚型
- IgG
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anti-Zinc Finger Protein 828 (ZNF828) (AA 1-812) antibody
ZNF828 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (AA 261-310) antibodyZNF828 适用: 人, 小鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (AA 563-812) antibodyZNF828 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (Middle Region) antibodyZNF828 适用: 人, 小鼠, 大鼠, 马, 犬, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ZNF828 (Zinc Finger Protein 828 (ZNF828))
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别名
- CHAMP1
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背景
- CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
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UniProt
- Q96JM3
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途径
- Maintenance of Protein Location
抗原
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