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WRNIP1 抗体

WRNIP1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7004728
发货至: 中国
  • 抗原 See all WRNIP1 抗体
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    适用
    • 25
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 24
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This WRNIP1 antibody is un-conjugated
    应用范围
    • 24
    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human WRNIP1
    亚型
    IgG
    Top Product
    Discover our top product WRNIP1 Primary Antibody
  • 应用备注
    IHC 1:50-1:100, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.96 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    别名
    WRNIP1 (WRNIP1 产品)
    别名
    WRNIP1 antibody, wrnip1 antibody, RP11-420G6.2 antibody, WHIP antibody, bA420G6.2 antibody, zgc:85976 antibody, 4833444L21Rik antibody, Wrnip antibody, Whip antibody, Werner helicase interacting protein 1 antibody, Werner helicase interacting protein 1 L homeolog antibody, ATPase WRNIP1 antibody, WRNIP1 antibody, wrnip1.L antibody, wrnip1 antibody, EDI_075920 antibody, CpipJ_CPIJ017857 antibody, PITG_07216 antibody, VDBG_02914 antibody, Wrnip1 antibody, PGTG_08805 antibody
    背景
    Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.
    UniProt
    Q96S55
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