WRNIP1 抗体
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北京 101111
Quick Overview for WRNIP1 抗体 (ABIN7004728)
抗原
See all WRNIP1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human WRNIP1
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亚型
- IgG
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anti-Werner Helicase Interacting Protein 1 (WRNIP1) (AA 67-116) antibody
WRNIP1 适用: 人, 小鼠, 大鼠, Cow, 猴, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Werner Helicase Interacting Protein 1 (WRNIP1) (N-Term) antibodyWRNIP1 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Werner Helicase Interacting Protein 1 (WRNIP1) (C-Term) antibodyVerified WRNIP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Werner Helicase Interacting Protein 1 (WRNIP1) (AA 403-665) antibodyWRNIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Werner Helicase Interacting Protein 1 (WRNIP1) (C-Term) antibodyWRNIP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Werner Helicase Interacting Protein 1 (WRNIP1) (N-Term) antibodyWRNIP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Werner Helicase Interacting Protein 1 (WRNIP1) (Internal Region) antibodyWRNIP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:100, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.96 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
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别名
- WRNIP1
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背景
- Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.
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UniProt
- Q96S55
抗原
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