HIPK3 抗体
Quick Overview for HIPK3 抗体 (ABIN7247966)
抗原
See all HIPK3 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human HIPK3
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亚型
- IgG
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anti-Homeodomain Interacting Protein Kinase 3 (HIPK3) (AA 841-1130) antibody
HIPK3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Homeodomain Interacting Protein Kinase 3 (HIPK3) (AA 1127-1156), (C-Term) antibodyHIPK3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3241 unconjugated
anti-Homeodomain Interacting Protein Kinase 3 (HIPK3) (Internal Region) antibodyHIPK3 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:300, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))
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别名
- HIPK3
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背景
- Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
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UniProt
- Q9H422
抗原
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