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Foxk1 抗体

This anti-Foxk1 antibody is a 兔 多克隆 antibody detecting Foxk1 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7247897
发货至: 中国

Quick Overview for Foxk1 抗体 (ABIN7247897)

抗原

See all Foxk1 抗体
Foxk1 (Forkhead Box K1 (Foxk1))

适用

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人, 小鼠

宿主

  • 41

克隆类型

  • 41
多克隆

标记

  • 30
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This Foxk1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human FOXK1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.5 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Foxk1 (Forkhead Box K1 (Foxk1))

    别名

    FOXK1

    背景

    The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 75 kDa

    UniProt

    P85037
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