Cullin 4A 抗体
Quick Overview for Cullin 4A 抗体 (ABIN7247885)
抗原
See all Cullin 4A (CUL4A) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human CUL4A
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亚型
- IgG
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anti-Cullin 4A (CUL4A) (AA 1-759) antibody
CUL4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) antibodyCUL4A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-100) antibodyCUL4A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-100) antibodyCUL4A 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H3 unconjugated
anti-Cullin 4A (CUL4A) (AA 1-759) antibodyCUL4A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 31-60), (N-Term) antibodyCUL4A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB33954 unconjugated
anti-Cullin 4A (CUL4A) antibodyCUL4A 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (Middle Region) antibodyCUL4A 适用: 人, 小鼠, 大鼠, 马, 兔, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (AA 1-61) antibodyCUL4A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4A (CUL4A) (N-Term) antibodyCUL4A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.62 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cullin 4A (CUL4A)
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别名
- CUL4A
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背景
- Cullin proteins assemble a large number of RING E3 ubiquitin ligases,participating in the proteolysis through the ubiquitin-proteasome pathway. Two cullin 4 (CUL4) proteins,CUL4A (87 kDa) and CUL4B(104 kDa),have been identified. The two CUL4 sequences are 83 % identical. They target certain proteins for degradation by binding protein DDB1 to form a CUL4-DDB1 ubiquitin ligase complex with DDB. They form two individual E3 ligases,DDB1-CUL4ADDB2 and DDB1-CUL4BDDB2 in this process. CUL4A appeared in both the nucleus and the cytosol,suggesting a more complex mechanism for entering the nucleus. CUL4B is localized in the nucleus and facilitates the transfer of DDB1 into the nucleus independently of DDB2.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 88 kDa
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UniProt
- Q13619
抗原
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