PPM1M 抗体
Our Local Distributor
北京 101111
Quick Overview for PPM1M 抗体 (ABIN7247633)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Antigen affinity purification
-
免疫原
- Fusion protein of human PPM1M
-
亚型
- IgG
-
-
-
-
应用备注
- IHC 1:100-1:300, ELISA 1:5000-1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.74 mg/mL
-
缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))
-
别名
- PPM1M
-
背景
- PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
-
UniProt
- Q96MI6
抗原
-