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NIPBL 抗体

This anti-NIPBL antibody is a 兔 多克隆 antibody detecting NIPBL in ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7246814
发货至: 中国

Quick Overview for NIPBL 抗体 (ABIN7246814)

抗原

See all NIPBL 抗体
NIPBL (Nipped-B like Protein (NIPBL))

适用

  • 16
  • 15
  • 5
人, 小鼠

宿主

  • 25
  • 3
  • 2
  • 1

克隆类型

  • 27
  • 4
多克隆

标记

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NIPBL antibody is un-conjugated

应用范围

  • 13
  • 13
  • 9
  • 9
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human NIPBL

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NIPBL (Nipped-B like Protein (NIPBL))

    别名

    NIPBL

    背景

    This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene.

    UniProt

    Q6KC79

    途径

    Sensory Perception of Sound, Stem Cell Maintenance
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