JPT1 抗体
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北京 101111
Quick Overview for JPT1 抗体 (ABIN7246790)
抗原
适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human JPT1
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亚型
- IgG
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anti-Jupiter Microtubule Associated Homolog 1 (JPT1) antibody
JPT1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB6065 unconjugated Recombinant Antibody
anti-Jupiter Microtubule Associated Homolog 1 (JPT1) (AA 2-154) antibodyJPT1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:40-1:200, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- JPT1 (Jupiter Microtubule Associated Homolog 1 (JPT1))
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别名
- JPT1
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背景
- Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
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UniProt
- Q9UK76
抗原
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