PNRC2 抗体
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北京 101111
Quick Overview for PNRC2 抗体 (ABIN7246772)
抗原
See all PNRC2 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human PNRC2
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亚型
- IgG
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anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 1-139) antibody
PNRC2 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (AA 71-120) antibodyPNRC2 适用: 人, 兔, 豚鼠, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (N-Term) antibodyPNRC2 适用: 人, 大鼠, 兔, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (N-Term) antibodyPNRC2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (Middle Region) antibodyPNRC2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 马, Cow, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Proline Rich Nuclear Receptor Coactivator 2 (PNRC2) (N-Term) antibodyPNRC2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 马, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.54 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PNRC2 (Proline Rich Nuclear Receptor Coactivator 2 (PNRC2))
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别名
- PNRC2
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背景
- Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery (PubMed:19150429). May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs (PubMed:19150429). Required for UPF1/RENT1 localization to the P-body (PubMed:19150429). Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Also acts as a nuclear receptor coactivator (PubMed:11574675). May play a role in controlling the energy balance between energy storage and energy expenditure (By similarity).
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UniProt
- Q9NPJ4
抗原
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