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GSKIP 抗体

This anti-GSKIP antibody is a 兔 多克隆 antibody detecting GSKIP in ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7246769
发货至: 中国

Quick Overview for GSKIP 抗体 (ABIN7246769)

抗原

See all GSKIP 抗体
GSKIP (GSK3B interacting protein (GSKIP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This GSKIP antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human GSKIP

    亚型

    IgG
  • 应用备注

    IHC 1:40-1:200, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GSKIP (GSK3B interacting protein (GSKIP))

    别名

    GSKIP

    背景

    This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

    UniProt

    Q9P0R6
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