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TPMT 抗体

This anti-TPMT antibody is a 兔 多克隆 antibody detecting TPMT in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7246526
发货至: 中国

Quick Overview for TPMT 抗体 (ABIN7246526)

抗原

See all TPMT 抗体
TPMT (Thiopurine S-Methyltransferase (TPMT))

适用

  • 46
  • 13
  • 13
  • 2
  • 2

宿主

  • 36
  • 10

克隆类型

  • 32
  • 14
多克隆

标记

  • 29
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TPMT antibody is un-conjugated

应用范围

  • 35
  • 21
  • 20
  • 7
  • 6
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human TPMT

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TPMT (Thiopurine S-Methyltransferase (TPMT))

    别名

    TPMT

    背景

    This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 28 kDa

    UniProt

    P51580
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