RNF111 抗体
Quick Overview for RNF111 抗体 (ABIN7246457)
抗原
See all RNF111 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Antigen affinity purification
-
免疫原
- Fusion protein of human RNF111
-
亚型
- IgG
-
-
anti-Ring Finger Protein 111 (RNF111) (AA 1-108) antibody
RNF111 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Ring Finger Protein 111 (RNF111) (AA 1-985) antibodyRNF111 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 111 (RNF111) (AA 1-985) antibodyRNF111 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 111 (RNF111) (C-Term) antibodyRNF111 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC 1:50-1:300, ELISA 1:5000-1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.84 mg/mL
-
缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- RNF111 (Ring Finger Protein 111 (RNF111))
-
别名
- RNF111
-
背景
- The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
-
UniProt
- Q6ZNA4
抗原
-
