C8orf4 抗体
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北京 101111
Quick Overview for C8orf4 抗体 (ABIN7246439)
抗原
See all C8orf4 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human C8orf4
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亚型
- IgG
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应用备注
- IHC 1:40-1:200, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.96 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
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别名
- C8orf4
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背景
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
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UniProt
- Q9NR00
抗原
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