TUBGCP4 抗体
Quick Overview for TUBGCP4 抗体 (ABIN7004071)
抗原
See all TUBGCP4 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human TUBGCP4
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亚型
- IgG
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anti-Tubulin, gamma Complex Associated Protein 4 (TUBGCP4) (AA 203-309) antibody
TUBGCP4 适用: 人 ELISA, WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, gamma Complex Associated Protein 4 (TUBGCP4) (AA 1-666) antibodyTUBGCP4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tubulin, gamma Complex Associated Protein 4 (TUBGCP4) (AA 1-666) antibodyTUBGCP4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, gamma Complex Associated Protein 4 (TUBGCP4) (Internal Region) antibodyTUBGCP4 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tubulin, gamma Complex Associated Protein 4 (TUBGCP4) (Internal Region) antibodyTUBGCP4 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))
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别名
- TUBGCP4
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背景
- This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 76 kDa
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UniProt
- Q9UGJ1
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途径
- M Phase
抗原
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