NARF 抗体
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北京 101111
Quick Overview for NARF 抗体 (ABIN7246325)
抗原
See all NARF 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of human NARF
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亚型
- IgG
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anti-Nuclear Prelamin A Recognition Factor (NARF) antibody
NARF 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Prelamin A Recognition Factor (NARF) (AA 10-41) antibodyNARF 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Prelamin A Recognition Factor (NARF) (C-Term) antibodyNARF 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Prelamin A Recognition Factor (NARF) (AA 395-444) antibodyNARF 适用: 人, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Prelamin A Recognition Factor (NARF) (AA 323-372) antibodyNARF 适用: 人, 马, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Prelamin A Recognition Factor (NARF) (AA 1-100) antibodyNARF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7D9 unconjugated
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应用备注
- IHC 1:50-1:300, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.56 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NARF (Nuclear Prelamin A Recognition Factor (NARF))
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别名
- NARF
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背景
- Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.
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UniProt
- Q9UHQ1
抗原
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