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IMPA1 抗体

This anti-IMPA1 antibody is a 兔 多克隆 antibody detecting IMPA1 in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7246232
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IMPA1 抗体 (ABIN7246232)

抗原

See all IMPA1 抗体
IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))

适用

  • 34
  • 14
  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 30
  • 4

克隆类型

  • 31
  • 3
多克隆

标记

  • 16
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This IMPA1 antibody is un-conjugated

应用范围

  • 14
  • 8
  • 6
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human IMPA1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))

    别名

    IMPA1

    背景

    This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 30 kDa

    UniProt

    P29218
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