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UNC13B 抗体

This anti-UNC13B antibody is a 兔 多克隆 antibody detecting UNC13B in ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7245965
发货至: 中国

Quick Overview for UNC13B 抗体 (ABIN7245965)

抗原

See all UNC13B 抗体
UNC13B (Unc-13 Homolog B (UNC13B))

适用

  • 32
  • 12
  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 2
  • 1

克隆类型

  • 41
  • 1
多克隆

标记

  • 23
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UNC13B antibody is un-conjugated

应用范围

  • 28
  • 21
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human UNC13B

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.6 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    UNC13B (Unc-13 Homolog B (UNC13B))

    别名

    UNC13B

    背景

    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

    UniProt

    O14795

    途径

    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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