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ZNF354A 抗体

This anti-ZNF354A antibody is a 兔 多克隆 antibody detecting ZNF354A in ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7245911
发货至: 中国

Quick Overview for ZNF354A 抗体 (ABIN7245911)

抗原

See all ZNF354A 抗体
ZNF354A (Zinc Finger Protein 354A (ZNF354A))

适用

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人, 小鼠, 大鼠

宿主

  • 11
  • 4

克隆类型

  • 12
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多克隆

标记

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This ZNF354A antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Fusion protein of human ZNF354A

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ZNF354A (Zinc Finger Protein 354A (ZNF354A))

    别名

    ZNF354A

    背景

    ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Krüppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.

    UniProt

    O60765

    途径

    Sensory Perception of Sound
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