MOBKL1A 抗体
Quick Overview for MOBKL1A 抗体 (ABIN7245845)
抗原
See all MOBKL1A (MOB1B) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Full length fusion protein
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亚型
- IgG
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anti-MOB Kinase Activator 1B (MOB1B) (AA 2-216) antibody
MOB1B 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 177-206), (C-Term) antibodyMOB1B 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB12538 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) antibodyMOB1B 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 3G9 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 101-150) antibodyMOB1B 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (AA 120-216) antibodyMOB1B 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (Center) antibodyMOB1B 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MOB Kinase Activator 1B (MOB1B) (C-Term) antibodyMOB1B 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.8 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MOBKL1A (MOB1B) (MOB Kinase Activator 1B (MOB1B))
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别名
- MOB1B
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背景
- The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 25 kDa
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UniProt
- Q7L9L4
抗原
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