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KIAA0556 抗体

This anti-KIAA0556 antibody is a 兔 多克隆 antibody detecting KIAA0556 in ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7245491
发货至: 中国

Quick Overview for KIAA0556 抗体 (ABIN7245491)

抗原

KIAA0556

适用

人, 小鼠

宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This KIAA0556 antibody is un-conjugated

应用范围

ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human KIAA0556

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.96 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KIAA0556

    别名

    KIAA0556

    背景

    This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia.

    UniProt

    O60303
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