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- 抗原 See all IRGC 抗体
- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRGC antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human IRGC
- 亚型
- IgG
- Top Product
- Discover our top product IRGC Primary Antibody
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anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibody
IRGC 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibodyIRGC 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibodyIRGC 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.78 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
- 别名
- IRGC (IRGC 产品)
- 背景
- Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
- UniProt
- Q6NXR0
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