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GRIK2 抗体

This anti-GRIK2 antibody is a 兔 多克隆 antibody detecting GRIK2 in ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7003616
发货至: 中国

Quick Overview for GRIK2 抗体 (ABIN7003616)

抗原

See all GRIK2 抗体
GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

适用

  • 42
  • 22
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  • 10
  • 6
  • 6
  • 6
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  • 4
  • 4
  • 4
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 41
  • 2

克隆类型

  • 40
  • 3
多克隆

标记

  • 28
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRIK2 antibody is un-conjugated

应用范围

  • 31
  • 15
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  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human GRIK2

    亚型

    IgG
  • 应用备注

    IHC 1:30-1:150, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.78 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

    别名

    GRIK2

    背景

    GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2) is a Protein Coding gene. Diseases associated with GRIK2 include Autosomal Recessive Non-Syndromic Intellectual Disability and Spinocerebellar Ataxia 11. Among its related pathways are CREB Pathway and Presynaptic function of Kainate receptors. GO annotations related to this gene include protein homodimerization activity and ubiquitin protein ligase binding. An important paralog of this gene is GRIK3.Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

    UniProt

    Q13002

    途径

    Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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