GALR2 抗体
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北京 101111
Quick Overview for GALR2 抗体 (ABIN7245017)
抗原
See all GALR2 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human GALR2
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亚型
- IgG
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anti-Galanin Receptor 2 (GALR2) (AA 51-150) antibody
GALR2 适用: 人, 小鼠, 大鼠 WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Transmembrane Domain) antibodyGALR2 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (C-Term) antibodyGALR2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 282-387) antibodyGALR2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (Internal Region) antibodyVerified GALR2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Galanin Receptor 2 (GALR2) (AA 223-235) antibodyGALR2 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:300, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.14 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GALR2 (Galanin Receptor 2 (GALR2))
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别名
- GALR2
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背景
- GALR2 (Galanin Receptor 2) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and galanin receptor activity. An important paralog of this gene is GALR3.Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
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UniProt
- O43603
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途径
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
抗原
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