EPS15 抗体
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北京 101111
Quick Overview for EPS15 抗体 (ABIN7244873)
抗原
See all EPS15 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human EPS15
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亚型
- IgG
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应用备注
- IHC 1:50-1:300, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.5 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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别名
- EPS15
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背景
- This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15) is a Protein Coding gene. Diseases associated with EPS15 include Vaccinia. Among its related pathways are Notch signaling pathway (KEGG) and HIV Life Cycle. GO annotations related to this gene include calcium ion binding and SH3 domain binding. An important paralog of this gene is EPS15L1.
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UniProt
- P42566
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途径
- EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
抗原
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