HIRA 抗体 (AA 251-350)
Quick Overview for HIRA 抗体 (AA 251-350) (ABIN700345)
抗原
See all HIRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-350
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HIRA/DGGR1
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亚型
- IgG
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anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 250-550) antibody
HIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-1017) antibodyHIRA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (pThr555) antibodyHIRA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 374C6a unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: Saccharomyces cerevisiae WB 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 601-650) antibodyHIRA 适用: 人, 小鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal WC15 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal WC119-2H11 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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别名
- HIRA
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背景
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Synonyms: DGCR1, DGGR 1, DGGR1, DiGeorge critical region gene 1, HIR, HIR histone cell cycle regulation defective homolog A, HIRA, HIRA protein, HIRA_HUMAN, Protein HIRA, TUP 1, TUP1, TUP1 like enhancer of split protein 1, TUP1-like enhancer of split protein 1, TUPLE 1, TUPLE1.
Background: The HIRA gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in flies, yeast and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
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基因ID
- 7290
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途径
- Chromatin Binding
抗原
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