C14orf169 + NO66 抗体
Quick Overview for C14orf169 + NO66 抗体 (ABIN7244582)
抗原
See all C14orf169 + NO66 (C14orf169) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human C14orf169
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亚型
- IgG
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anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (AA 1-641) antibody
C14orf169 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (Internal Region) antibodyVerified C14orf169 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (AA 67-116) antibodyC14orf169 适用: 人, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) antibodyC14orf169 适用: 人 DB 宿主: 小鼠 Monoclonal 3354C5a unconjugated
anti-Chromosome 14 Open Reading Frame 169 (C14orf169) (N-Term) antibodyC14orf169 适用: 人, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.8 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
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别名
- C14orf169
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背景
- Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation.
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UniProt
- Q9H6W3
抗原
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