PNOC 抗体
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北京 101111
Quick Overview for PNOC 抗体 (ABIN7243640)
抗原
See all PNOC 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human PNOC
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亚型
- IgG
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anti-Prepronociceptin (PNOC) (AA 12-187) antibody
PNOC 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Prepronociceptin (PNOC) (AA 96-168) antibodyPNOC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Prepronociceptin (PNOC) (AA 126-151) antibodyPNOC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21156 unconjugated
anti-Prepronociceptin (PNOC) antibodyPNOC 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prepronociceptin (PNOC) (AA 20-176) antibodyPNOC 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Prepronociceptin (PNOC) (AA 12-181) antibodyPNOC 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.4 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PNOC (Prepronociceptin (PNOC))
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别名
- PNOC
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背景
- Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.
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NCBI登录号
- NP_006219
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UniProt
- Q13519
抗原
-
