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B-Cell Linker 抗体

This anti-B-Cell Linker antibody is a 兔 多克隆 antibody detecting B-Cell Linker in ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7243052
发货至: 中国

Quick Overview for B-Cell Linker 抗体 (ABIN7243052)

抗原

See all B-Cell Linker (BLNK) 抗体
B-Cell Linker (BLNK)

适用

  • 107
  • 75
  • 45
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 117
  • 8
  • 1

克隆类型

  • 116
  • 10
多克隆

标记

  • 54
  • 7
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This B-Cell Linker antibody is un-conjugated

应用范围

  • 113
  • 52
  • 36
  • 26
  • 21
  • 20
  • 19
  • 10
  • 8
  • 6
  • 4
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human BLNK

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.6 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    B-Cell Linker (BLNK)

    别名

    BLNK

    背景

    This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.

    分子量

    50 kDa

    NCBI登录号

    NP_001107566

    UniProt

    Q8WV28

    途径

    BCR Signaling
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